ChemInform Abstract: Waol A (I), trans-Dihydrowaol A (II), and cis-Dihydrowaol A (III): Polyketide-Derived γ-Lactones from a Volutella Species.

Authors :: El‐Elimat, Tamam
Figueroa, Mario
Raja, Huzefa A.
Adcock, Audrey F.
Kroll, David J.
Swanson, Steven M.
Wani, Mansukh C.
Pearce, Cedric J.
Oberlies, Nicholas H.
Source :: ChemInform. Nov2013, Vol. 44 Issue 46, pno-no. 1p.
Publication Year :: 2013
Abstract: The γ-lactones (I) and (II) are tested against two cancer cell lines, whereas compound (I) displays moderate cytotoxic activity against the SW-620 cancer cell line, compound (II) shows no activity. [ABSTRACT FROM AUTHOR]

Subjects :: *POLYKETIDES
*LACTONES
*CANCER cells
*CELL lines
*CELL-mediated cytotoxicity
*PYRAN derivatives
*ANTINEOPLASTIC agents

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