Simplified syntheses of the water-soluble chiral shift reagents Sm-(R)-pdta and Sm-(S)-pdta.

Authors :: Hrubá, Lucie
Buděšínský, Miloš
Pícha, Jan
Jiráček, Jiří
Vaněk, Václav
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Nov2013, Vol. 54 Issue 47, p6296-6297. 2p.
Publication Year :: 2013
Abstract: Abstract: The chiral shift reagents Sm-(R)-pdta and Sm-(S)-pdta, which are based on (R)- or (S)-1,2-diaminopropane-N,N,N′,N′-tetraacetic acid were synthesized from easily accessible compounds in three simple steps, which makes the method suitable for laboratory-scale production. In addition, a new and efficient method for the preparation of pure anhydrous (R)- or (S)-1,2-diaminopropane-N,N,N′,N′-tetraacetic acid was developed. [Copyright &y& Elsevier]

Subjects :: *CHEMICAL reagents
*CHIRALITY
*CHEMICAL synthesis
*DIAMINOPROPANE
*ACETIC acid
*ORGANIC chemistry

Language :: English
ISSN :: 00404039
Volume :: 54
Issue :: 47
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 91266359
Full Text :: https://doi.org/10.1016/j.tetlet.2013.09.009

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