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Modeling Proteome Networks with Range-Dependent Graphs.
- Source :
-
American Journal of PharmacoGenomics . 2003, Vol. 3 Issue 1, p1-4. 4p. 2 Graphs. - Publication Year :
- 2003
-
Abstract
- In this paper we consider the problem of characterizing and modeling large-scale protein-protein association networks using a class of range-dependent graphs which possess appropriate small world properties. These graphs may be employed in representing given association network using a maximum likelihood approach. This in turn annotates every observed association with its ‘range’, representing the tendency for such an association to be transitive. The application of a very rapidly developing field of graph theory to the emerging field of proetemics is novel and allows for a many-to-many relationship between individual proteins and groupings of proteins, which in turn may correspond to distinct functional behavior. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PROTEOMICS
*PROTEIN-protein interactions
*BIOMOLECULES
*GRAPH theory
*PROTEINS
Subjects
Details
- Language :
- English
- ISSN :
- 11752203
- Volume :
- 3
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- American Journal of PharmacoGenomics
- Publication Type :
- Academic Journal
- Accession number :
- 9048659
- Full Text :
- https://doi.org/10.2165/00129785-200303010-00001