Essential role of Gas6 for glomerular injury in nephrotoxic nephritis.

Authors :: Yanagita, Motoko
Ishimoto, Yoshikazu
Arai, Hidenori
Nagai, Kojiro
Ito, Tsuyoshi
Nakano, Toru
Salant, David J.
Fukatsu, Atsushi
Doi, Toshio
Kita, Toru
Source :: Journal of Clinical Investigation. 7/15/2002, Vol. 110 Issue 2, p239. 8p. 3 Black and White Photographs, 1 Diagram, 1 Graph.
Publication Year :: 2002
Abstract: Presents a study which examined the role of growth-arrest specific gene 6 (Gas6) in accelerated nephrotoxic nephritis (NTN) by constructing Gas6 mice. Characteristics of glomerular cell proliferation; Methods used; Expression of Gas6 during the proliferative phase of NTN; Generation and characterization of Gas6 mice.