Back to Search
Start Over
Synthesis and Antimalarial Bioassay of Quinine - Peptide Conjugates.
- Source :
-
Chemical Biology & Drug Design . Oct2013, Vol. 82 Issue 4, p361-366. 6p. - Publication Year :
- 2013
-
Abstract
- Amino acid and peptide conjugates of quinine were synthesized using microwave irradiation in 52-95% yields using benzotriazole methodology. The majority of these conjugates retain in vitro antimalarial activity with IC50 values below 100 n m, similar to quinine. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17470277
- Volume :
- 82
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Chemical Biology & Drug Design
- Publication Type :
- Academic Journal
- Accession number :
- 90465606
- Full Text :
- https://doi.org/10.1111/cbdd.12134