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Thymolipoma With Sebaceous Differentiation: A Hitherto Unreported Variant of Thymolipoma.
- Source :
-
International Journal of Surgical Pathology . Oct2013, Vol. 21 Issue 5, p526-530. 5p. - Publication Year :
- 2013
-
Abstract
- Thymolipoma is a very rare anterior mediastinal mass of thymic origin, accounting for only 2% to 10% of all thymic neoplasm. Histologically, the tumor is usually composed of adipose tissue interspersed with thymic tissues. We report a case of a 58-year-old man who presented with a few weeks history of shortness of breath, cough, and chest pain, found to have a retrocardiac infiltrate on chest X-ray. Computed tomography scan of the chest showed a large anterior mediastinal mass. Surgical excision revealed an ovoid fatty mass, which on histological examination displayed thymic tissue intermixed with lipomatous tissue consistent with a thymolipoma. Of note was the presence of a microscopic nodule of thymic epithelial proliferation with sebaceous differentiation and focal cylindroma-like architecture. Although sebaceous tissue has been rarely reported in thymic tissue, to the best of our knowledge, this is the first case report of sebaceous differentiation in a thymolipoma. [ABSTRACT FROM AUTHOR]
- Subjects :
- *THYMUS
*THYROID gland tumors
*ADIPOSE tissues
*CHEST pain
*COMPUTED tomography
Subjects
Details
- Language :
- English
- ISSN :
- 10668969
- Volume :
- 21
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- International Journal of Surgical Pathology
- Publication Type :
- Academic Journal
- Accession number :
- 90398086
- Full Text :
- https://doi.org/10.1177/1066896912473357