Fibrinogen.

Authors :: Arbustini, Eloisa
Narula, Nupoor
D'Armini, Andrea M.
Source :: Circulation. 9/17/2013, Vol. 128 Issue 12, p1276-1280. 5p.
Publication Year :: 2013
Abstract: The author presents information on fibrinogen. Fibrinogen, or coagulation factor I, is a main player in thrombus formation. It is split by thrombin to form fibrin, which is the most abundant component of a blood clot. It is a proinflammatory factor in autoimmune and inflammatory diseases, such as rheumatoid arthritis, vasculitides, inflammatory bowel disease and multiple sclerosis.