Application of the McDonald 2010 criteria for the diagnosis of multiple sclerosis in an Argentinean cohort of patients with clinically isolated syndromes.

The article presents a study which evaluated the new magnetic resonance imaging (MRI) criteria for multiple sclerosis (MS) diagnosis in patients having clinically isolated syndrome (CIS) in Buenos Aires, Argentina. New criteria accuracy, negative predictive value (NPV), positive predictive value (PPV), specificity and sensitivity were determined. The sub-analysis applied just to non-European descendants revealed a high level of accuracy for the new MRI criteria.