Individual and combined developmental toxicity assessment of bisphenol A and genistein using the embryonic stem cell test in vitro.

Highlights: [•] Bisphenol A and genistein were classified as weakly and strongly embryotoxic respectively in embryonic stem cell test. [•] The combined exposure effects of BPA and GEN were evaluated using a 4×4 full factorial design. [•] BPA and GEN have a synergistic effect on embryonic stem cells differentiation at lower dosages. [ABSTRACT FROM AUTHOR]