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Serum antibodies against native and denaturated hemagglutinin glycoproteins detected by ELISA as correlates of protection after influenza vaccination in healthy vaccinees and in kidney transplant recipients.

Authors :
Grund, S.
Pietzonka, S.
Michel, S.
Adams, O.
Source :
Journal of Virological Methods. Nov2013, Vol. 193 Issue 2, p558-564. 7p.
Publication Year :
2013

Abstract

Highlights: [•] Two ELISA assays are analyzed as correlates of immunity after influenza vaccination. [•] Antibodies against unfolded recombinant and against native hemagglutinin are detected. [•] Results are compared to microneutralization titers. [•] Healthy individuals and patients after kidney transplantation are investigated. [•] Both ELISA assays are correlated with microneutralization titers and can serve as markers of protection. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01660934
Volume :
193
Issue :
2
Database :
Academic Search Index
Journal :
Journal of Virological Methods
Publication Type :
Academic Journal
Accession number :
90203493
Full Text :
https://doi.org/10.1016/j.jviromet.2013.07.032