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Advances in the analysis of single mitochondria

Authors :
Fuller, Kathryn M
Arriaga, Edgar A
Source :
Current Opinion in Biotechnology. Feb2003, Vol. 14 Issue 1, p35. 7p.
Publication Year :
2003

Abstract

Mitochondria are both morphologically and functionally diverse, and this variety is thought to have important biological ramifications. The development of methods to probe the properties of individual mitochondria is therefore of utmost importance. Recent advances have been made using in situ microscopy techniques and methods to investigate isolated mitochondria, including flow cytometry, capillary electrophoresis, patch-clamping and optical trapping. Such techniques have been used to study metabolism, mitochondrial calcium homeostasis, mitochondrial membrane potential, apoptosis, and other properties. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
09581669
Volume :
14
Issue :
1
Database :
Academic Search Index
Journal :
Current Opinion in Biotechnology
Publication Type :
Academic Journal
Accession number :
9011585
Full Text :
https://doi.org/10.1016/S0958-1669(02)00008-3