Back to Search Start Over

Anticancer cyclometalated complexes of platinum group metals and gold.

Authors :
Cutillas, Natalia
Yellol, Gorakh S.
de Haro, Concepción
Vicente, Consuelo
Rodríguez, Venancio
Ruiz, José
Source :
Coordination Chemistry Reviews. Oct2013, Vol. 257 Issue 19/20, p2784-2797. 14p.
Publication Year :
2013

Abstract

Highlights: [•] Cyclometalated complexes of noble metals are promising anticancer prodrugs. [•] These compounds show improved stability and enhanced cytotoxicity. [•] Cyclometalated compounds are suitable for rational drug design. [•] Besides DNA, protein/enzyme interactions represent a major mode of action. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
00108545
Volume :
257
Issue :
19/20
Database :
Academic Search Index
Journal :
Coordination Chemistry Reviews
Publication Type :
Academic Journal
Accession number :
89998421
Full Text :
https://doi.org/10.1016/j.ccr.2013.03.024