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Anticancer cyclometalated complexes of platinum group metals and gold.
- Source :
-
Coordination Chemistry Reviews . Oct2013, Vol. 257 Issue 19/20, p2784-2797. 14p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] Cyclometalated complexes of noble metals are promising anticancer prodrugs. [•] These compounds show improved stability and enhanced cytotoxicity. [•] Cyclometalated compounds are suitable for rational drug design. [•] Besides DNA, protein/enzyme interactions represent a major mode of action. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00108545
- Volume :
- 257
- Issue :
- 19/20
- Database :
- Academic Search Index
- Journal :
- Coordination Chemistry Reviews
- Publication Type :
- Academic Journal
- Accession number :
- 89998421
- Full Text :
- https://doi.org/10.1016/j.ccr.2013.03.024