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Solid-Phase Synthesis of Substituted Alkynes Using the Nicholas Reaction.

Authors :
Cassel, Johan A.
Leue, Stefanie
Gachkova, Natalie I.
Kann, Nina C.
Source :
Journal of Organic Chemistry. 12/27/2002, Vol. 67 Issue 26, p9460. 4p. 1 Diagram, 2 Charts.
Publication Year :
2002

Abstract

The first example of a Nicholas reaction on solid phase is reported, involving the reaction of cobalt complexes of polymer-bound alkynols with different nucleophiles in the presence of a Lewis acid, to form carbon-oxygen or carboncarbon bonds. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00223263
Volume :
67
Issue :
26
Database :
Academic Search Index
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
8975715
Full Text :
https://doi.org/10.1021/jo026156u