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Two receptors are involved in the central functions of kynurenic acid under an acute stress in neonatal chicks.

Authors :
Yoshida, J.
Shigemura, A.
Ogino, Y.
Denbow, D.M.
Furuse, M.
Source :
Neuroscience. Sep2013, Vol. 248, p194-200. 7p.
Publication Year :
2013

Abstract

Highlights: [•] Kynurenic acid (KYNA) had sedative and hypnotic effects during stress in chicks. [•] KYNA is an endogenous antagonist of both the α7nACh and NMDA receptors. [•] KYNA inhibited NMDA receptor subgroup containing the NR2A and NR2B subunits. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03064522
Volume :
248
Database :
Academic Search Index
Journal :
Neuroscience
Publication Type :
Academic Journal
Accession number :
89615871
Full Text :
https://doi.org/10.1016/j.neuroscience.2013.06.005