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Activation-induced cytidine deaminase auto-activates and triggers aberrant gene expression.
- Source :
-
FEBS Letters . Aug2013, Vol. 587 Issue 16, p2487-2492. 6p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] Ectopic expression of AID perturbed normal gene expression. [•] AID specifically activated methylated reporter constructs including that for Pax5. [•] Ectopically expressed AID (with Gadd45) induced aberrant endogenous Pax5 expression. [•] The Pax5 expressed in response to AID and Gadd45 was associated with the AID promoter. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00145793
- Volume :
- 587
- Issue :
- 16
- Database :
- Academic Search Index
- Journal :
- FEBS Letters
- Publication Type :
- Academic Journal
- Accession number :
- 89607262
- Full Text :
- https://doi.org/10.1016/j.febslet.2013.06.028