CYP1A1 genetic polymorphism and polycyclic aromatic hydrocarbons on pulmonary function in the elderly: Haplotype-based approach for gene–environment interaction.

Highlights: [•] PAH exposure may be an important risk factor for reduced lung function in the elderly. [•] Individuals with a certain haplotype of CYP1A1 are susceptible to that risk. [•] This study suggests haplotype-based gene–environment interaction in lung function. [ABSTRACT FROM AUTHOR]