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MAGE-C1/CT7 spontaneously triggers a CD4+ T-cell response in multiple myeloma patients.

Authors :
Nuber, N
Curioni-Fontecedro, A
Dannenmann, S R
Matter, C
von Boehmer, L
Atanackovic, D
Knuth, A
van den Broek, M
Source :
Leukemia (08876924). Aug2013, Vol. 27 Issue 8, p1767-1769. 3p. 2 Graphs.
Publication Year :
2013

Abstract

The article presents a study which examines the presence of CT7 T cells in the bone marrow of patients with multiple myeloma (MM). It analyzes the CT7-specific CD4+ T cells in peripheral blood mononuclear cell of MM patients through in vitro stimulation approach. Findings reveal that CD4+ CT7 T-cell responses in patients were controlled by T regulatory cells (Tregs).

Details

Language :
English
ISSN :
08876924
Volume :
27
Issue :
8
Database :
Academic Search Index
Journal :
Leukemia (08876924)
Publication Type :
Academic Journal
Accession number :
89595917
Full Text :
https://doi.org/10.1038/leu.2013.31