Development and validation of a sensitive LC–MS/MS method for the determination of fenoterol in human plasma and urine samples.

Authors :: Sanghvi, M.
Ramamoorthy, A.
Strait, J.
Wainer, I.W.
Moaddel, R.
Source :: Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences. Aug2013, Vol. 933, p37-43. 7p.
Publication Year :: 2013
Abstract: Highlights: [•] Developed an LC–MS/MS method for the determination of fenoterol enantiomers. [•] Improved quantitation limit from 2ng/ml to 50pg/ml over existing methods. [•] Enantioselective competitive interaction affects fenoterol presystemic sulfation. [Copyright &y& Elsevier]

Subjects :: *FENOTEROL
*LIQUID chromatography-mass spectrometry
*BLOOD plasma
*URINALYSIS
*ENANTIOMERS
*SULFATION

Language :: English
ISSN :: 15700232
Volume :: 933
Database :: Academic Search Index
Journal :: Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences
Publication Type :: Academic Journal
Accession number :: 89436691
Full Text :: https://doi.org/10.1016/j.jchromb.2013.06.020

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