Solid-phase Petasis multicomponent reaction for the generation of β-lactams 3-substituted with non-proteinogenic α-amino acids.

Authors :: Cornier, Patricia G.
Delpiccolo, Carina M.L.
Boggián, Dora B.
Mata, Ernesto G.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Aug2013, Vol. 54 Issue 35, p4742-4745. 4p.
Publication Year :: 2013
Abstract: Abstract: An efficient protocol for the rapid generation of libraries of biologically promising β-lactams is described. Key step is a solid-phase based multicomponent Petasis reaction. [Copyright &y& Elsevier]

Subjects :: *SOLID-phase synthesis
*MULTIPHASE flow
*CHEMICAL reactions
*LACTAMS
*SUBSTITUTION reactions
*AMINO acids

Language :: English
ISSN :: 00404039
Volume :: 54
Issue :: 35
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 89349369
Full Text :: https://doi.org/10.1016/j.tetlet.2013.06.112

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