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Curcumin inhibits oxLDL-induced CD36 expression and foam cell formation through the inhibition of p38 MAPK phosphorylation.

Authors :
Min, Kyoung-jin
Um, Hee Jung
Cho, Kyung-Hyun
Kwon, Taeg Kyu
Source :
Food & Chemical Toxicology. Aug2013, Vol. 58, p77-85. 9p.
Publication Year :
2013

Abstract

Highlights: [•] Curcumin blocks foam cell formation in oxLDL-treated RAW 264.7 cells. [•] Curcumin inhibits oxLDL-induced CD36 expression. [•] Curcumin reduces oxLDL-induced PPAR-γ expression. [•] Curcumin inhibits oxLDL-induced CD36 and PPAR-γ expression via inhibition of p38 MAPK signaling. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
02786915
Volume :
58
Database :
Academic Search Index
Journal :
Food & Chemical Toxicology
Publication Type :
Academic Journal
Accession number :
89311088
Full Text :
https://doi.org/10.1016/j.fct.2013.04.008