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Curcumin-containing liposomes stabilized by thin layers of chitosan derivatives.
- Source :
-
Colloids & Surfaces B: Biointerfaces . Sep2013, Vol. 109, p307-316. 10p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] Cationic, hydrophobic and cationic–hydrophobic derivatives of chitosan were obtained and characterized. [•] Curcumin-containing liposomes were successfully stabilized by effective coating with these derivatives. [•] Liposomes coated with cationic–hydrophobic chitosan are most promising for curcumin delivery. [•] Such coated liposomes easily penetrate cell membrane and release curcumin in a controlled manner. [•] These curcumin-loaded liposomal systems are non-toxic for normal cells, but toxic for murine melanoma. [Copyright &y& Elsevier]
- Subjects :
- *CURCUMIN
*LIPOSOMES
*CHITOSAN
*CHEMICAL derivatives
*MELANOMA
*HYDROPHOBIC compounds
Subjects
Details
- Language :
- English
- ISSN :
- 09277765
- Volume :
- 109
- Database :
- Academic Search Index
- Journal :
- Colloids & Surfaces B: Biointerfaces
- Publication Type :
- Academic Journal
- Accession number :
- 89275540
- Full Text :
- https://doi.org/10.1016/j.colsurfb.2013.03.059