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3-Aminophenyl boronic acid-functionalized CuInS2 quantum dots as a near-infrared fluorescence probe for the determination of dopamine.
- Source :
-
Biosensors & Bioelectronics . Sep2013, Vol. 47, p379-384. 6p. - Publication Year :
- 2013
-
Abstract
- Abstract: Water-soluble CuInS2 ternary quantum dots (QDs) capped by mercaptopropionic acid were directly synthesized in aqueous solution. Consequently, the CuInS2 QDs were covalently linked to 3-aminophenyl boronic acid molecules to form the 3-aminophenyl boronic acid-functionalized CuInS2 QDs (F-CuInS2 QDs). The F-CuInS2 QDs had a fairly symmetric fluorescence emission centered at 736nm that was in the near-infrared region (NIR). The F-CuInS2 QDs containing boronic acid functional groups were reactive toward vicinal diols to form five- or six-member cyclic esters in an alkaline aqueous solution. The reaction would cause the fluorescence quenching, which could be used as a fluorescence probe for the determination of dopamine (DA). This assay could also probe other vicinal diols such as catechol, pyrogallol, and gallate, based on the fluorescence quenching of the F-CuInS2 QDs, and this assay was nearly unaffected by other phenol compounds such as phenol, resorcinol, and hydroquinone without the vicinal diol structures. The developed F-CuInS2 QDs were applied to the detection of DA in human serum samples with satisfactory results. Therefore, this experment provided a simple and sensitve NIR fluorescence probe for the detection of DA, catechol, pyrogallol, and gallate. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 09565663
- Volume :
- 47
- Database :
- Academic Search Index
- Journal :
- Biosensors & Bioelectronics
- Publication Type :
- Academic Journal
- Accession number :
- 89271372
- Full Text :
- https://doi.org/10.1016/j.bios.2013.03.055