Direct synthesis of pyrrolo[2,1-a]isoquinolines by 1,3-dipolar cycloaddition of stabilized isoquinolinium N-ylides with vinyl sulfonium salts.

Authors :: An, Jing
Yang, Qing-Qing
Wang, Qiang
Xiao, Wen-Jing
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jul2013, Vol. 54 Issue 29, p3834-3837. 4p.
Publication Year :: 2013
Abstract: Abstract: A direct and efficient synthesis of 2,3-unsubstituted 1-acylpyrrolo[2,1-a]isoquinolines is described. The 1,3-dipolar cycloaddition of stabilized isoquinolinium N-ylides with vinyl sulfonium salts features simple experimental procedures, mild conditions, and moderate to good yields. [Copyright &y& Elsevier]

Subjects :: *ISOQUINOLINE synthesis
*RING formation (Chemistry)
*YLIDES
*SULFONIUM compounds
*SALTS
*ACYL compounds

Language :: English
ISSN :: 00404039
Volume :: 54
Issue :: 29
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 89117278
Full Text :: https://doi.org/10.1016/j.tetlet.2013.05.053

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