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Blockade of interleukin-6 receptor suppresses inflammatory reaction and facilitates functional recovery following olfactory system injury.

Authors :
Kobayashi, Masayoshi
Tamari, Kengo
Miyamura, Tomotaka
Takeuchi, Kazuhiko
Source :
Neuroscience Research. Jul2013, Vol. 76 Issue 3, p125-132. 8p.
Publication Year :
2013

Abstract

Highlights: [•] Anti-IL-6R antibody decreased astrocytes and macrophages in damaged olfactory bulbs. [•] Anti-IL-6R antibody contributes to olfactory nerve regeneration morphologically. [•] Anti-IL-6R antibody contributes to functional recovery of the olfactory system. [•] Blockade of IL-6R could be a new treatment for traumatic olfactory dysfunction. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
01680102
Volume :
76
Issue :
3
Database :
Academic Search Index
Journal :
Neuroscience Research
Publication Type :
Academic Journal
Accession number :
89116814
Full Text :
https://doi.org/10.1016/j.neures.2013.03.015