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Aldol addition of dihydroxyacetone to N-Cbz-3-aminopropanal catalyzed by two aldolases variants in microreactors.

Authors :
Sudar, Martina
Findrik, Zvjezdana
Vasić-Rački, Đurđa
Clapés, Pere
Lozano, Carles
Source :
Enzyme & Microbial Technology. Jun2013, Vol. 53 Issue 1, p38-45. 8p.
Publication Year :
2013

Abstract

Highlights: [•] Aldol addition catalyzed by two aldolases was carried out in microreactor. [•] Three co-solvents were evaluated: ethyl acetate, acetonitrile and dimethylformamide. [•] High enzyme concentration results in higher conversion at lower residence time. [•] Enzyme inactivation occurs in microreactor and increases with residence time. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
01410229
Volume :
53
Issue :
1
Database :
Academic Search Index
Journal :
Enzyme & Microbial Technology
Publication Type :
Academic Journal
Accession number :
89104192
Full Text :
https://doi.org/10.1016/j.enzmictec.2013.03.013