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New trifluoromethyl quinolone derivatives: Synthesis and investigation of antimicrobial properties.
- Source :
-
Bioorganic & Medicinal Chemistry Letters . Jun2013, Vol. 23 Issue 11, p3225-3229. 5p. - Publication Year :
- 2013
-
Abstract
- Abstract: A series of quinolone derivatives, containing different heterocyclic amines were prepared. Synthesized compounds were evaluated for their in vitro antimicrobial activities against two Gram-positive bacteria, three Gram-negative bacteria as well as four fungi. All the derivatives showed good activity towards Gram-positive bacteria and less activity towards Gram-negative bacteria. They also showed moderate to comparable activity against Aspergillus niger and Candida albicans and low to moderate antifungal activity against Aspergillus fumigatus and Aspergillus flavus. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 0960894X
- Volume :
- 23
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Publication Type :
- Academic Journal
- Accession number :
- 89089917
- Full Text :
- https://doi.org/10.1016/j.bmcl.2013.03.120