Artificial enzyme activity from cyclodextrins with cyanohydrins on the secondary rim.

Authors :: Zhou, You
Pedersen, Christian M.
Bols, Mikael
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. May2013, Vol. 54 Issue 20, p2458-2461. 4p.
Publication Year :: 2013
Abstract: Abstract: The synthesis of two per-O-methylated cyclodextrins with one or two α-hydroxypropionitrile groups attached to the secondary rim is described. The two new cyanohydrins are found to catalyse the hydrolysis of 4-nitrophenyl β-D-glucopyranoside in a buffer solution at pH 8.0 with a rate acceleration of up to 1770. [Copyright &y& Elsevier]

Subjects :: *ENZYME activation
*CYCLODEXTRINS
*CYANOHYDRINS
*ACCELERATION (Mechanics)
*CATALYSIS

Language :: English
ISSN :: 00404039
Volume :: 54
Issue :: 20
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 89067961
Full Text :: https://doi.org/10.1016/j.tetlet.2013.02.091

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