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Mammalian galectins bind Galactoseβ1–4Fucose disaccharide, a unique structural component of protostomial N-type glycoproteins.
- Source :
-
Biochemical & Biophysical Research Communications . Jul2013, Vol. 436 Issue 3, p509-513. 5p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] Human galectin-1 preferentially binds to Galβ1–4Fuc over Galβ1–4GlcNAc. [•] Other mammalian galectins show substantial affinity toward Galβ1–4Fuc disaccharide. [•] Galβ1–4Fuc-OMe inhibits hGal-1−ligand interaction more effectively than lactose. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 436
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 88992964
- Full Text :
- https://doi.org/10.1016/j.bbrc.2013.05.135