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HMGB1 recruits myeloid derived suppressor cells to promote peritoneal dissemination of colon cancer after resection.
- Source :
-
Biochemical & Biophysical Research Communications . Jun2013, Vol. 436 Issue 2, p156-161. 6p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] HMGB1 in the peritoneal cavity of mice after surgical trauma was detected. [•] HMGB1 in the peritoneal cavity recruited myeloid derived suppressor cells. [•] Blocking HMGB1 reduced the recruitment of myeloid derived suppressor cells. [•] The recruited MDSCs favor postoperative peritoneal metastasis of colon cancer. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 436
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 88988096
- Full Text :
- https://doi.org/10.1016/j.bbrc.2013.04.109