HMGB1 recruits myeloid derived suppressor cells to promote peritoneal dissemination of colon cancer after resection.

Highlights: [•] HMGB1 in the peritoneal cavity of mice after surgical trauma was detected. [•] HMGB1 in the peritoneal cavity recruited myeloid derived suppressor cells. [•] Blocking HMGB1 reduced the recruitment of myeloid derived suppressor cells. [•] The recruited MDSCs favor postoperative peritoneal metastasis of colon cancer. [ABSTRACT FROM AUTHOR]