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Development of Akt-activated GSK3β inhibitory peptide.
- Source :
-
Biochemical & Biophysical Research Communications . May2013, Vol. 434 Issue 4, p735-739. 5p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] We designed a novel peptide sequence to inhibit GSK3beta. [•] Activation of the peptide requires the kinase activities of Akt and GSK3beta. [•] GSK3beta is inhibited by the peptide only in response to the insulin signaling. [•] We propose a novel concept to develop a drug. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 434
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 88985426
- Full Text :
- https://doi.org/10.1016/j.bbrc.2013.03.103