BRIP1 variations analysis reveals their relative importance as genetic susceptibility factor for cervical cancer.

Highlights: [•] The rs4986764 (exon 18) was significantly associated with cervix cancer. [•] Another significant association was observed for rs4986763 (exon 20). [•] Significantly more T–T–T haplotypes resided in block 1 were found in controls. [•] Cervical cancer tissues with rs4986764 C/C had the lowest level of BRIP1. [•] We provide first evidence of BRIP1 to the genetic susceptibility of cervical cancer. [ABSTRACT FROM AUTHOR]