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Black Blood MRI in Suspected Large Artery Primary Angiitis of the Central Nervous System.
- Source :
-
Journal of Neuroimaging . Jul2013, Vol. 23 Issue 3, p379-383. 5p. - Publication Year :
- 2013
-
Abstract
- ABSTRACT OBJECTIVES Single case reports suggest that black blood MRI (T1-weighted fat and blood suppressed sequences with and without contrast injection; BB-MRI) may visualize intracranial vessel wall contrast enhancement (CE) in primary angiitis of the central nervous system (PACNS). In this single-center observational pilot study we prospectively investigated the value of BB-MRI in the diagnosis of large artery PACNS. METHODS Patients with suspected large artery PACNS received a standardized diagnostic program including BB-MRI. Vessel wall CE was graded (grade 0-2) by two experienced readers blinded to clinical data and correlated to the final diagnosis. RESULTS Four of 12 included patients received a final diagnosis of PACNS. All of them showed moderate (grade 1) to strong (grade 2) vessel wall CE at the sites of stenosis. A moderate (grade 1) vessel wall CE grade was also observed in 6 of the remaining 8 patients in whom alternative diagnoses were made: arteriosclerotic disease ( n= 4), intracranial dissection ( n= 1), and Moyamoya disease ( n= 1). CONCLUSIONS Our pilot study demonstrates that vessel wall CE is a frequent finding in PACNS and its mimics. Larger trials will be necessary to evaluate the utility of BB-MRI in the diagnostic workup of PACNS. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10512284
- Volume :
- 23
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of Neuroimaging
- Publication Type :
- Academic Journal
- Accession number :
- 88824269
- Full Text :
- https://doi.org/10.1111/j.1552-6569.2012.00743.x