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A roundabout route to gene therapy.
- Source :
-
Nature Genetics . Apr2002, Vol. 30 Issue 4, p345. 2p. - Publication Year :
- 2002
-
Abstract
- The uniqueness of the mitochondrial genome presents a number of obstacles to the successful use of gene therapy for the treatment of mitochondrial DNA disease. A new study shows that the effects of a pathogenic mutation in a human mitochondrial gene can be rectified by expressing an engineered wildtype copy of the gene in the nucleus. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MITOCHONDRIAL pathology
*GENE therapy
*GENETIC engineering
Subjects
Details
- Language :
- English
- ISSN :
- 10614036
- Volume :
- 30
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Nature Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 8782098
- Full Text :
- https://doi.org/10.1038/ng0402-345