Detrusor-sphincter dyssynergia: presentation of four cases and literature

Detrusor-sphincter dyssynergia is responsible for major impairement and is factor for social and professional activity repercussions.Methods : We have studied the clinical and urodynamic finding in four patients (two men and two women) with detrusor-sphincter dyssynergia. Mean age is 36 years (26–44 years). Dyssynergia was secondary to tuberculosis meningitis in one case, surgery for rectal adenocarcinoma in one case, tight vertebral canal in one case and in one case the cause is indeterminate. The detrusor-sphincter dyssynergia were treated by autocatheterism in two cases, antibiotherapy antituberculosis associated with an anticholinergic drugs in one case and by alpha-blockers agent in another.Results : Quasi-complete salvage of the motor deficit and the dysfonctional voiding in a patient treated by antibiotherapy antituberculosis associated with an anticholinergic drugs. As well, maid evolution in patient treated by alpha-blockers agent and who practice self catheterization.Conclusion : Optimal treatment is unknown, and the existence of several cures indicated the limit of all therapeutic methods. [Copyright &y& Elsevier]