Oligopaints: highly efficient, bioinformatically designed probes for fluorescence in situ hybridization.

A conference paper about variation of the Fluorescence in situ hybridization (FISH), a technique used to detect and localize the presence of specific DNA sequences on chromosomes is presented. It mentions that the new method uses Oligopaints and Polymerase Chain Reaction (PCR) for generating FISH probes from complex DNA libraries. It mentions that use of bioinformatic tools has made it possible to perform hybridizations between Oligopaints and RNA and genomic DNA at the site of transcription.