Silica-Supported Ionic Liquid Si-[SbSipim][PF 6 ]: An Efficient Catalyst for the Synthesis of 3,4-Dihydropyrimidine-2-(1H)-ones.

Silica-supported sulfonic acid–functional ionic liquid (Si-[SbSipim][PF6]) was found to be an effective catalyst for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones via a one-pot, three-component Biginelli reaction. The catalyst could be easily separated and reused six times without noticeable reduction inactivity. The process was simple and proceeded in excellent yields. Supplemental materials are available for this article. Go to the publisher's online edition ofSynthetic Communications® to view the free supplemental file. [ABSTRACT FROM AUTHOR]