Short-term haemodynamic effects of BQ-123, a selective endothelin ET(A)-receptor antagonist, in chronic heart failure.

Authors :: Cowburn, Peter J.
Cleland, John G. F.
McArthur, John D.
MacLean, Margaret R.
McMurray, John J.V.
Dargie, Henry J.
Cowburn, P J
Cleland, J G
McArthur, J D
MacLean, M R
McMurray, J J
Dargie, H J
Source :: Lancet. 7/18/1998, Vol. 352 Issue 9123, p201-202. 2p. 4 Graphs.
Publication Year :: 1998
Abstract: Focuses on the increased plasma concentrations of endothelin-1 (ET1) in patients with chronic heart failure. How the vasoconstrictor action of ET1 is mediated; Benefical effects of Bosentan, an non-selective ET-alpha/ET-beta-receptor antagonist; Study of ten patients with stable chronic heart failure; Findings; Conclusions.

Full Text Access

Tools