Back to Search
Start Over
Very small photoluminescent gold nanoparticles for multimodality biomedical imaging
- Source :
-
Biotechnology Advances . May2013, Vol. 31 Issue 3, p362-368. 7p. - Publication Year :
- 2013
-
Abstract
- Abstract: An original synthesis method based on X-ray irradiation produced gold nanoparticles (AuNPs) with two important properties for biomedical research: intense visible photoluminescence and very high accumulation in cancer cells. The nanoparticles, coated with MUA (11-mercaptoundecanoid acid), are very small (1.4nm diameter); the above two properties are not present for even slightly larger sizes. The small MUA-AuNPs are non-cytotoxic (except for very high concentrations) and do not interfere with cancer cell proliferation. Multimodality imaging using visible light fluorescence and X-ray microscopy is demonstrated by tracing the nanoparticle-loaded tumor cells. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 07349750
- Volume :
- 31
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Biotechnology Advances
- Publication Type :
- Academic Journal
- Accession number :
- 86157628
- Full Text :
- https://doi.org/10.1016/j.biotechadv.2012.05.005