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Granulocyte colony-stimulating-factor-producing hepatocellular carcinoma with extensive sarcomatous changes: report of a case.
- Source :
-
Surgery Today . Apr2013, Vol. 43 Issue 4, p439-445. 7p. - Publication Year :
- 2013
-
Abstract
- This report describes a rare case of hepatocellular carcinoma (HCC) producing granulocyte colony-stimulating factor (G-CSF). A 46-year-old male with chronic hepatitis B, who presented with fever, general malaise, loss of appetite, and weight loss, had a huge liver mass in the portal region. He had marked granulocytosis and his serum level of G-CSF was elevated. Complete tumor resection was performed, and the pathological assessment of the resected specimen revealed HCC with extensive sarcomatous changes and immunohistochemical staining for G-CSF and G-CSF receptor. Only a few cases of G-CSF-producing HCC have been reported, and this is the first case of G-CSF-producing HCC that also expressed G-CSF receptor. [ABSTRACT FROM AUTHOR]
- Subjects :
- *TUMORS
*LIVER cancer
*GRANULOCYTES
*WEIGHT loss
*PATHOLOGY
Subjects
Details
- Language :
- English
- ISSN :
- 09411291
- Volume :
- 43
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Surgery Today
- Publication Type :
- Academic Journal
- Accession number :
- 86145206
- Full Text :
- https://doi.org/10.1007/s00595-012-0202-0