Large Meningioma in an Infant.

Background Histologically confirmed meningiomas in first year of life are quite rare. However, review of the sporadic cases in the literature reported meningioma in infants. Those have unique features in common. Case presentation An 11 month-old Iranian male infant presented with a several weeks history of decrease in movement of his right sided upper and lower extremities. Brain MRI revealed a large well-defined extra axial, Dural-based mass lesion, which is contained solid and cystic components. It is originated from falx, and showed intense contrast enhancement. The patient underwent a central craniotomy. The mass was removed sub totally. Microscopic examination of the specimen revealed a meningioma. Radiotherapy was deferred because of the young age. Patient follow up at 4 months later showed that the child was well. Conclusion Pediatric meningiomas show a higher frequency of cyst formation in compared with adult meningiomas. In addition, they show more frequent sarcomatous changes, which is male predominance. Absence of dural based attachment and higher incidence of intraventricular location were seen. [ABSTRACT FROM AUTHOR]