Electrochemical determination of norepinephrine on the membrane of silver nanoparticles doped poly-glycine eliminating the interference of ascorbic acid.

The silver nanoparticles doped poly-glycine composite membrane was prepared by cyclic voltammetry on the surface of the glassy carbon electrode (GCE). The morphology and electrochemical properties were characterized by scanning electron microscopy and cyclic voltammetry, respectively, and in detail, the electrochemical behaviors of the norepinephrine (NE) on this membrane were studied. The results showed that the membrane had good catalytic properties for the oxidative-reductive reaction of NE. NE had a couple of sensitive oxidative-reductive current peaks. The reductive peak currents were linearly with its concentration in the range of 1.90 × 10 to 7.00 × 10 and 7.00 × 10 to 1.00 × 10 mol l, and the linear regressive equations were i (A) = 3.73 × 10 + 0.70 C (mol l), i (A) = 9.83 × 10 + 0.12 C (mol l), respectively, with the relate coefficient ( r) of 0.9926 and 0.9944. The detection limit was 1.2 × 10 mol l (S/N = 3), which could be used to determine the content of NE and at the same time, eliminate the interference of the ascorbic acid (AA). The proposed method had high sensitivity, good selectivity and stability. [ABSTRACT FROM AUTHOR]