Aryl-Heteroaryl Derivatives as Novel Wake-Promoting Agents.

Authors :: Lesur, Brigitte
Lin, Yin G.
Marcy, Val R.
Aimone, Lisa D.
Gruner, John
Bacon, Edward R.
Chatterjee, Sankar
Source :: Chemical Biology & Drug Design. Mar2013, Vol. 81 Issue 3, p429-432. 4p. 2 Diagrams, 2 Charts, 1 Graph.
Publication Year :: 2013
Abstract: In search of a next generation molecule to the novel wake-promoting agent modafinil, a series of aryl-heteroayl-derived wakefulness enhancing agents (in rats) was developed. From this work, compound 16 was separated into its enantiomers to profile them individually. [ABSTRACT FROM AUTHOR]