Click-generated triazole based ferrocene-carbohydrate bioconjugates: A highly selective multisignalling probe for Cu(II) ions.

Two Cu-specific colorimetric sensors, based on ferrocene-carbohydrate bioconjugates, 2, CHONFe and 3, CHONFe were designed and synthesized in good yields. Both the compounds, 2 and 3, behave as very selective and sensitive chromogenic and electrochemical chemosensor for Cu ion in aqueous environment (CHCN/HO (2:8, v/ v). The analytical detection limit (ADL) for receptor 2 was 7.5 × 10 M. The considerable changes in their absorption spectra of 2 and 3 are accompanied by the appearance of a new low energy (LE) peak at 630 nm ( 2: ε = 1600 M cm and 3: 822 M cm). This is further accompanied by a strong colour change from yellow to dark green that allows the prospective for 'naked eye' detection of Cu ion. [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR]