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An Alternative Isovaleryl CoA Biosynthetic Pathway Involving a Previously Unknown 3-Methylglutaconyl CoA Decarboxylase.
- Source :
-
Angewandte Chemie International Edition . Jan2013, Vol. 52 Issue 4, p1304-1308. 5p. - Publication Year :
- 2013
-
Abstract
- Take a detour: An alternative pathway to synthesize isovaleryl coenzyme A (CoA) has recently been suggested in myxobacteria, which is highly active when leucine is limited. Each enzymatic step of this unprecedented route has now been characterized and a novel 3‐methylglutaconyl CoA decarboxylase identified that has apparently evolved from CoA transferases. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14337851
- Volume :
- 52
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Angewandte Chemie International Edition
- Publication Type :
- Academic Journal
- Accession number :
- 84782945
- Full Text :
- https://doi.org/10.1002/anie.201207984