İnfantil dönemde böbrek yetmezliği gelişen primer hiperokzalüri: İki olgu sunumu.

Primary hyperoxaluria is a rare genetic disorder in glyoxylate metabolism that leads to systemic overproduction of oxalate. The disorder results in overproduction and excessive urinary excretion of oxalate, causing recurrent urolithiasis and nephrocalcinosis. As glomerular filtration rate declines due to progressive renal involvement, oxalate accumulates leading to systemic oxalosis. We, herein report two cases of primary hyperoxaluria with renal failure in infancy. [ABSTRACT FROM AUTHOR]