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Dexamethasone suppresses iNOS gene expression by regulating I-...B... and inhibiting NF-...B.

Authors :
de Vera, Michael E.
Taylor, Bradley S.
Qi Wang
Shapiro, Richard A.
Billiar, Timothy R.
Geller, David A.
Source :
American Journal of Physiology. Dec97 Part 1 of 3, Vol. 273 Issue 6, pG1290. 7p. 10 Black and White Photographs, 5 Graphs.
Publication Year :
1997

Abstract

Presents a study which examined the molecular mechanisms underlying glucocorticoids (GC) downregulation of nitric oxide synthase (iNOS) gene expression in rat hepatocytes. Impact of GC on cytokines and immunomodulatory genes; Methodology used to conduct the study; Results of the study.

Details

Language :
English
ISSN :
00029513
Volume :
273
Issue :
6
Database :
Academic Search Index
Journal :
American Journal of Physiology
Publication Type :
Academic Journal
Accession number :
84073