An Eficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic Nanocrystalline Fe3O4.

An efficient approach for one-pot three-component reaction of aromatic amines, α,β-unsaturated aldehydes and β-keto esters using magnetic nanocrystalline Fe3O4 as a catalyst has been described. The corresponding 1,4-dihydropyridines are obtained in good yields under mild conditions. In addition, the catalyst can be recovered with a magnet and reused at least five consecutive cycles without appreciable loss of its catalytic activity. [ABSTRACT FROM AUTHOR]