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Palladium-Catalyzed Synthesis of 1,2,3,4-Tetrahydro-5H-2-benzazepin-5-ones.

Authors :
Okuro, Kazumi
Alper, Howard
Source :
Synlett. Oct2012, Vol. 23 Issue 17, p2531-2533. 3p.
Publication Year :
2012

Abstract

Palladium-catalyzed intermolecular cyclocarbonylation of 2-iodobenzylamines with Michael acceptors produces 1,2,3,4- tetrahydro-5H-2-benzazepin-5-one derivatives in moderate to good yields. This methodology enables the direct preparation of highly functionalized 1,2,3,4-tetrahydro-5H-2-benzazepin-5-ones from readily available starting materials. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09365214
Volume :
23
Issue :
17
Database :
Academic Search Index
Journal :
Synlett
Publication Type :
Academic Journal
Accession number :
82592570
Full Text :
https://doi.org/10.1055/s-0032-1317183