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Product inhibition of the hepatitis C virus NS3 protease.
- Source :
-
Biochemistry . 06/23/98, Vol. 37 Issue 25, p8899. 7p. 1 Color Photograph, 2 Charts, 5 Graphs. - Publication Year :
- 1998
-
Abstract
- States that the nonstructural protein NS3 of the hepatitis C virus (HCV), harbors a serine protease domain that is responsible for most of the processing events of the nonstructural region of the polyprotein. How inhibition of NS3 affects the disease caused by HCV; Methodology used to conduct inhibition process; Identification of an important determinant for product binding; Discussion on findings.
- Subjects :
- *HEPATITIS C virus
*SERINE proteinases
*CHEMICAL structure
Subjects
Details
- Language :
- English
- ISSN :
- 00062960
- Volume :
- 37
- Issue :
- 25
- Database :
- Academic Search Index
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 822161
- Full Text :
- https://doi.org/10.1021/bi980313v