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Wickerols A and B: novel anti-influenza virus diterpenes produced by Trichoderma atroviride FKI-3849
- Source :
-
Tetrahedron . Nov2012, Vol. 68 Issue 45, p9267-9271. 5p. - Publication Year :
- 2012
-
Abstract
- Abstract: Wickerols A and B were produced by a fungus, Trichoderma atroviride FKI-3849. Wickerol A showed potent anti-influenza virus activity against strain A/PR/8/34 (H1N1), whereas wickerol B exhibited weaker impact. The anti-influenza virus spectrum between wickerols A and B was different. The cyclization mechanism of the wickerol carbon-skeleton was investigated by incorporation of 13C-labeled acetate. A pathway through the verticillyl cation was predicted. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 68
- Issue :
- 45
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 80180333
- Full Text :
- https://doi.org/10.1016/j.tet.2012.08.066